Acologix. **

Actimis Pharmaceuticals, Inc.
Development of small molecule therapeutics for respiratory and inflammatory disorders.

aFRAXis, Inc.
The company is developing a dendritic spine analysis platform and applying this technology to the development of new drugs for these disease indications.

Angstrom. *

Anosys, Inc. **
Biotechnology company developing and commercializing an artificial chromosome expression system. Aquired by Chromos Molecular Systems Inc. (“Chromos”; TSX:CHR).

Arriva Pharmaceuticals. *

Avidia Research Institute, Inc. *
Avidia uses proprietary protein technology to develop therapeutic products. Aquired by Amgen, Inc (NASDAQ:AMGN)

BioSeek **

Bridge Pharmaceuticals (Beijing, China) *
Bridge Laboratories is a preclinical contract research organization (CRO) that provides US-level regulatory-compliant drug development services globally.

Canaan Partners *
Global venture capital firm that invests in people who turn visionary ideas into valuable and significant technology & healthcare companies.

Catalyst Biosciences, Inc. *
Harnesses the power of these enzymes as bio-pharmaceuticals by redirecting them to degrade specific proteins that promote disease.

Cellerant Therapeutics, Inc. ***
Develops novel, cell-based medicine as a treatment for chemotherapy- and radiation-induced neutropenia as well as for Acute Radiation Syndrome.

Connetics Corporation **
Advanced therapies and topical delivery technologies. Merged with Stiefel Laboratories Inc in 2006 to combine technology, expertise and pharmaceutical experience to treat skin diseases.

Depomed, Inc.
A specialty pharmaceutical company focused on enhancing pharmaceutical products.

Helicon ***
Therapeutics to treat disorders of cognition.

Iconix Pharmaceuticals, Inc. *
Applies novel and proprietary genomic technologies to profile candidate drug compounds in early discovery through to pre-clinical development

La Jolla Pharmaceutical Company *
The Company's leading product in development is Riquent®, which is designed to treat lupus renal disease by preventing or delaying renal flares.

Myogen, Inc. *
Is a developer of small molecule therapeutics to treat cardiovascular diseases. Myogen is now a subsidiary of Gilead Sciences, Inc.

Novalar Pharmaceuticals, Inc. *
OraVerse™, has been developed to rapidly reverse the lingering and debilitating lip and tongue numbness associated with local dental anesthesia

Nuon Therapeutics *
Nuon Therapeutics is a clinical stage biotechnology company developing medicines to treat autoimmune disease and pain.

Nuvelo, Inc. *
Dedicated to improving the lives of patients through the discovery, development and commercialization of novel drugs for acute cardiovascular disease, cancer and other debilitating medical conditions.

Omeros Corporation
A clinical-stage biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation and disorders of the central nervous system.

Ossur Americas
A leading global company in non-invasive orthopedics. http://www.ossur.com/?pageid=12501

Osprey Pharmaceuticals, Inc.
Developes a series of novel fusion protein therapeutics which selectively target and neutralize activated leukocytes that are implicated in a variety of inflammatory and immune disorders.

PDxRX, Inc.
Specialty pharmaceutical company focused on pediatric subspecialty markets.

Plexus Vaccines, Inc.
Biotechnology company employing rational drug design principles for vaccine discovery and development. Acquired by SIGA Technologies, Inc.

PRA International
PRA is one of the world's leading global clinical development organizations

Prometheus Laboratories, Inc.
Prometheus primarily focuses on the treatment, diagnosis and detection of gastrointestinal, autoimmune and inflammatory diseases and disorders.

John Wayne Cancer Institute

Xoma
Therapeutic antibody discovery and development (NASD: XOMA).

Zygem Corporation
Produces DNA extraction and detection products, molecular biology enzymes and individual enzymes and diagnostics.

Celtor Biosystems *

LumMed Corporation *

Alpha Therapeutic Corporation *
Working in the fields of transfusion, blood banking and clinical analysis. Now a division of Grifols USA.

Amira Medical
Manufacturer of diabetes monitoring products. Aquired by Roche.

Anergen, Inc. *
treatment of autoimmune diseases. Aquired by Corixa Corporation followed by a merger with GlaxoSmithKline.

Athena Neurosciences, Inc.
Develops drugs and drug-delivery systems through its subsidiaries. Aquired by Elan Pharmaceuticals (NYSE: ELN)

Aventis Gencell *
Leading global pharmaceutical company that discovers, develops, produces and markets innovative therapies that enhance people’s lives. Aventis merged with Sanofi (NYSE: SNY & EURONEXT: SAN)

Aviron, Inc
Monoclonal antibody therapies for cancer. Aquired by MedImmune.

Baxter Biotech, Inc.
Provides therapeudics for hemophilia, immune disorders, kidney disease, cancer, trauma and other conditions (NYSE: BAX).

Berlex Biosciences, Inc.
Therapeutics for human and animal health. Aquired by Bayer to form Bayer Healthcare Pharmaceuticals.

BioGenex Laboratories, Inc.
BioGenex is an innovator and leader in the field of immunohistochemistry.

BioMedicines, Inc. *
Biopharmaceutical company developing therapies to ensure the best treatment outcome by optimizing patient convenience and adherence. Aquired by Intarcia Therapeutics, Inc.

Boston Scientific/Target
Boston Scientific’s mission is to improve the quality of patient care and the productivity of health care delivery through the development and advocacy of less-invasive medical devices and procedures.

Celtrix Pharmaceuticals, Inc. *
A biopharmaceutical company developing novel therapeutics for the treatment of seriously debilitating, degenerative conditions primarily associated with severe trauma, chronic diseases and aging.

Centaur Pharmaceuticals, Inc.
The 45th largest pharmaceutical company in India in prescription sales generating more than 50 million prescriptions per year. Centaur brands are exported to over 50 countries worldwide.

Collagen Corporation
Of Palo Alto, Calif., makes Zyderm and Zyplast, which are injected under the skin to smooth facial wrinkles and scars. Acquired In 1999 by INAMED Aesthetics Corporation followed by an acquisition by Allergan.

Coulter Pharmaceuticals, Inc.
Specialized in therapeutic antibodies and targeted oncologics platforms. Merged with Corixa Corporation in 2000 followed by a merger with GlaxoSmithKline.

Coulter Pharmaceuticals.

Cygnus, Inc.
Developed, manufactured and commercialized new and improved glucose-monitoring devices. The Company recently entered into a settlement agreement with Ortho-McNeil Pharmaceutical, Inc. in which Cygnus received $4 million in cash. Cygnus filed for dissolution in 2005 with the Secretary of State in Delaware.

Digital Gene Technologies, Inc.
A genomics company focused on bioinformatics and large scale tissue-wide gene expression studies, acquired by Neurome, Inc in 2004.

Emergency Medical Technologies (of Rivivant Corporation)
Aims to improve resuscitation outcomes by developing and marketing products that deliver; Superior clinical performance, Rapid therapy, Meaningful information, Higher user confidence, and Economic value.

Fluid Propulsion Technologies (now Aerogen, Inc.)
Develops and manufactures products for pulmonary drug delivery. The Company develops and commercializes a patent-protected system for aerosolizing liquids into a droplet size spray without pressure.

Genelabs Technologies, Inc.
A biopharmaceutical company focused on the discovery and development of pharmaceutical products to improve human health.

Hall Surgical (division of ZIMMER)
Manufacturer of orthopedic products and instruments. Includes detailed company profile, product and service specifications for medical professionals

Hyseq Pharmaceuticals, Inc. *
Develop and commercialize new treatments for human disease based upon its proprietary collection of rare and novel genes. Aquired by Nuvelo, Inc.

Inhale Therapeutics, Inc. (now Nektar Therapeutics, Inc.) *
Biopharmaceutical company that develops and enables differentiated therapeutics with its industry-leading PEGylation and pulmonary drug development platforms.

Mentor Corporation
Breast, face and body aesthetics.

Orquest, Inc.
A leader in orthobiologics. Acquired by DePuySpine Inc.

Pangea Pharmaceuticals/ZYCOS
Focuses on the commercialization of therapeutic proteins for the treatment of chronic diseases, such as its patented Leukocyte Population Modulators. Acquired by Zycos which was aquired by MGI pharma.

Paradigm Biosciences, Inc.
Develops novel therapeutics and vaccine adjuvants for synthetic versions of certain naturally occurring steroid hormones.

Pharmacyclics

Progenitor Cell Therapy, L.L.C. *
Progenitor Cell Therapy, LLC is a client-based cell therapy services company that supports the development of cellular therapies

SangStat Medical
Discover, develop and market high value therapeutic products in immunology, hematology/oncology and auto- immune disorders. Acquired by Genzyme Corporation

SciClone Pharmaceuticals, Inc.
Develops and markets products targeted for treatment of cancer and diseases such as hepatitis B and C, cystic fibrosis and immune system disorders

Signature Biosciences, Inc.
Multipole coupling spectroscopy (MCS) to study protein structure

Synpac (NC) Inc. *
Pompe disease treatment.

Synteni, Inc.
Synteni pioneered the use of DNA microarrays for the genomic revolution. Acquired by Incyte Genomics, Inc.

Syntex Pharmaceuticals.

Thermolase Corporation *
The principal activities of the Group were the manufacturing and marketing of skin-care, bath-and-body products, and the marketing of dietary supplements. Now part of Thermo Fisher Scientific.

Tularik, Inc. *
Lead medications for cancer and inflammatory disease. Acquired by AMGEN, Inc.

Valentis, Inc.
Specialty pharmaceutical company dedicated to the development and commercialization of therapeutic products for urological disorders. Acquired by Urigen Pharmaceutials.

VaxGen, Inc.
Development, manufacture and commercialization of biologic products for the prevention and treatment of human infectious disease.

VIVUS, Inc.
VIVUS currently has clinical development programs that target diseases of obesity, diabetes, and sexual health.

XOMA Corporation.

Zyomyx, Inc.
Development and commercializes proprietary protein analysis platforms.

Berlex Laboratories.

CODON.

Desmos.

Microcide Pharmaceuticals *

Paradigm Biosciences.

Revivant/EMS.

SyStemix *

Therex Corporation.

Triton Bioscience.